A sequel to the full-length CG animation feature Biohazard: Degeneration based upon the Biohazard (known on the western market as Resident Evil) series of games.

United States Special Agent Leon S. Kennedy sneaks into a small Eastern European country to verify rumors that Bio Organic Weapons (B.O.W.s) are being used in war. Right after his infiltration, the U.S. government orders him to leave immediately. Determined to uncover the truth, Leon ignores the order and enters the battlefield to end the chain of tragedies caused by the B.O.W.s. (Source: IMDB)

The Umbrella Incident that took place in Raccoon City was ended with the eradication of the deadly virus by a missile attack ordered by the government. As its operations were suspended on a global scale, Umbrella Corporation stock plummeted. This serious blow to the business giant resulted in its complete dissolution. 7 years later, at an airport somewhere in the United States. An ordinary autumn afternoon. One zombie is unleashed into this peaceful scene to attack everyone. In the airport starting to fill up with the undead, the horrific disaster is about to be repeat itself...The story is set to take place 7 years after the events depicted in the Biohazard and Biohazard 2 games (Resident Evil and Resident Evil 2 on the western market) featuring Leon S. Kennedy and Claire Redfield (both of who were the protagonists in Biohazard 2).

The story is set in autumn 2005, one year after Resident Evil 4 game took place. Due to an as of yet unexplained reason, zombies appear in a United States airport. The release of the zombies leads to danger of an outbreak.

The film will have a completely original story, and will feature characters from multiple games in the series, including Chris Redfield, Rebecca Chambers, and Leon Kennedy. CAPCOM producer Hiroyuki Kobayashi (Resident Evil 4, Sengoku Basara) is supervising the project.

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It is the year 2035, a world filled with advanced science and technology, sophisticated computer systems, audio/video multimedia converstions,world government unification, network wars by hackers, and the future world controlled by one huge multinational company. A 14-year old named Kang Maru, a boy with excellent manuevering skills in a RESTOL simulation game, was chosen by GEONOID, a company with the task of protecting the earth against natural calamities, to pilot RESTOL 03, one of the 5 RESTOLs, to rescue people in different calamities. Now, he and his teammates faces different challenges in their duty, including being hacked their space-based rescue station R-SAT.

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